主講人：周豔雙

　　時間：2019年8月23日 15:30

　　地點：廣州生物醫藥與健康研究院（A326）

　　主持人：陳可實 副研究員

Achievement introduction: we addressed a new selection strategy in which the selective elimination of mitochondria is dependent on organellar topology. We found that populations of mitochondria undergo different topological transformations under serum starvation, either swelling or forming donut shapes. Swollen mitochondria are associated with mitochondrial membrane potential dissipation and PRKN recruitment, which promote their selective elimination, while the donut topology maintains mitochondrial membrane potential and helps mitochondria resist autophagy.